Phenotypic screening is an ideal strategy for the discovery of novel bioactive molecules.Using a customized high-throughput screening (HTS) assay employing primary T lymphocytes, we screened a small library of 4,398 compounds with unknown biological function/target to identify compounds eliciting immunomodulatory properties Jumper and discovered a
Taxonomic Revision of Cirrodrilus makinoi (Annelida: Clitellata: Branchiobdellida) with a Redescription of C. homodontus
Cirrodrilus makinoi (Yamaguchi, 1934) has not been identified since it was originally described from the Japanese crayfish, Cambaroides japonicus (De Haan, 1841) on Hokkaido Jumper Island, northern Japan.A critical morphological comparison of the original and new material of C.makinoi with those of closely related C.tsugarensis Gelder and Ohtaka, 2
Endometriosis Associated Striated Muscle Changes: Simulating Tumor
Endometriosis in the abdominal wall can be a diagnostic challenge, both clinically and pathologically.We are describing a case of abdominal wall endometriosis where regenerative muscle cells are florid.The cells are small and polygonal in shape, arranged in groups, and intersecting through differentiated skeletal muscle.Cells have pink cytoplasm an